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Submissions from 2014

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Raman Microspectroscopy for the Early Detection of Pre-Malignant Changes in Cervical Tissue, Nosheen Rashid, Haq Nawaz, Kelvin W. Poon, Franck Bonnier, Salih Bakhiet, Cara Martin, John O'Leary, Hugh Byrne, and Fiona Lyng

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Cell survival and DNA damage in normal prostate cells irradiated out-of-field, L. Shields, I. Vega-Carrascal, S. Singleton, F. M. Lyng, and B. McClean

Submissions from 2013

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Raman Spectroscopic Mapping for the Analysis of Solar Radiation Induced Skin Damage, Hugh Byrne, Syed Mehmood Ali, Franck Bonnier, K. Ptasinski, Helen Lambkin, Kathleen Flynn, and Fiona Lyng

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Apoptosis is Signalled Early by Low Doses of Ionizing Radiation in a Radiation-Induced Bystander Effect, Hayley Furlong, Carmel Mothersill, Fiona Lyng, and Orla Howe

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Utilising Caging Techniques to Investigate Metal Assimilation in Nucella lapillus, Mytilus edulis and Crassostrea gigas at Three Irish Coastal Locations, Michelle Giltrap, Ailbhe Macken, Maria Davoren, Evin McGovern, Barry Foley, Martin Larsen, Jonathan White, and Brendan McHugh

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Cell Death Pathways in Directly Irradiated Cells and Cells Exposed to Medium from Irradiated Cells, K.K. Jella, Amaya Garcia, Brendan McClean, Hugh Byrne, and Fiona Lyng

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Vibrational spectroscopy in sensing radiobiological effects: analyses of targeted and non-targeted effects in human keratinocytes, Aidan Meade, Orla L. Howe, Valerie Unterreiner, Ganesh Sockalingum, Hugh Byrne, and Fiona Lyng

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Generation of Intracellular Reactive Oxygen Species and Genotixity Effect to Exposure of Nanosized Polyamidoamine (PAMAM) Dendrimers in PLHC-1 Cells in Vitro, Pratap Naha and Hugh Byrne

Submissions from 2012

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Identifying and Localizing Intracellular Nanoparticles Using Raman Spectroscopy, Jennifer Dorney, Franck Bonnier, Amaya Garcia, Alan Casey, Gordon Chambers, and Hugh Byrne

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The Effect of Genetic Background and Dose on Non-Targeted Effects of Radiation, Sarah Irons, Virginia Sierra, Deborah Bowler, Kim Chapman, Stefania MIliti, Fiona Lyng, and Munira Kadhim

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The Importance of Serum Serotonin Levels in the Measurement of Radiation-Induced Bystander Cell Death in HaCaT Cells, Fiona Lyng, Maxine Desplanques, K.K. Jella, Amaya Garcia, and Brendan McClean

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A laboratory inter-comparison of the importance of serum serotonin levels in the measurement of a range of radiation-induced bystander effects: Overview of study and results presentation., Fiona Lyng; C. Mothersill; F. Antonelli; V. Dini; M. Kämäräinen,; and B. Schilling-Tóth

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Quantitative Reagent-Free Detection Of Fibrinogen Levels In Human Blood Plasma Using Raman Spectroscopy, Kelvin Poon, Fiona Lyng, Peter Knief, Orla L. Howe, Aidan Meade, James Curtin, Hugh Byrne, and Joseph Vaughan

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Impaired Cleanance and Enhanced Pulmonary Inflammatory/Fibrotic Response to Carbon Nanotubes in Myeloperoxidase-Deficient Mice, Anna A. Shvedova, Alexandr A. Kapralov, Wei Hong Feng, Elena R. Kisin, Ashley R. Murray, Robert R. Mercer, Claudette M. St. Croix, Megan A. Lang, Simon C. Watkins, Nagarjun V. Konduru, Brett L. Allen, Jennifer Conroy, Gregg P. Kotchey, Bashir M. Mohamed, Aidan Meade, Yuri Volkov, Alexander Star, Bengt Fadeel, and Valerian E. Kagan

Submissions from 2011

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Understanding the Molecular Information Contained in Principal Component Analysis of Vibrational Spectra of Biological Systems, Franck Bonnier and Hugh Byrne

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In Vitro Analysis of Immersed Human Tissues by Raman Microspectroscopy, Franck Bonnier, A. Mehmood, Peter Knief, Aidan Meade, Helen Lambkin, Kathleen Flynn, V. McDonagh, C. Healy, T. C. Lee, Fiona Lyng, and Hugh Byrne

In-vitro screening of organotin compounds and sediment extracts for cytotoxicity to fish cells, Michelle Giltrap, Ailbhe Macken, Brendan McHugh, Evin McGovern, Barry Foley, and Maria Davoren

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Water-soluble bis(1,10-phenanthroline) Octanedioate Cu2+ and Mn2+ Complexes with Unprecedented Nano and Picomolar in Vitro Cytotoxicity: Promising Leads for Chemotherapeutic Drug Development, Andrew Kellett, Mark O'Connor, Malachy McCann, Orla Howe, Alan Casey, Pauraic McCarron, Kevin Kavanagh, Mary McNamara, Sean Kennedy, Donald May, Philip Skell, Denis O'Shea, and Michael Devereux

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Reactive Oxygen Species-induced Release of Signalling Factors in Irradiated Cells Triggers Membrane Signalling and Calcium Influx in Bystander Cells., Fiona Lyng, Orla L. Howe, and Brendan McClean

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Comparison of Subcellular Responses for the Evaluation and Prediction of the Chemotherapeutic Response to Cisplatin in Lung Adenocarcinoma using Raman Spectroscopy, Haq Nawaz, Franck Bonnier, Aidan Meade, Fiona Lyng, and Hugh Byrne

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Correlation of p16INK4A Expression and HPV Copy Number with Cellular FTIR Spectroscopic Signatures of Cervical Cancer Cells, Kamila Ostrowska, Amaya Garcia, Aidan Meade, Alison Malkin, Ifeoluwapo Okewumi, John O’Leary, Cara Martin, Hugh Byrne, and Fiona Lyng

Submissions from 2010

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An Investigation of the RWPE Prostate Derived Family of Cell Lines Using FTIR Spectroscopy, M. Baker, Colin Clarke, D. Demoulin, J. Nicolson, Fiona Lyng, Hugh Byrne, C. Hart, M. Brown, N. Clarke, and P. Gardner

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Imaging Live Cells Grown on a Three Dimensional Collagen Matrix Using Raman Microspectroscopy, Franck Bonnier, Peter Knief, Basil Lim, Aidan Meade, Jennifer Dorney, Kunal Bhattacharya, Fiona Lyng, and Hugh Byrne

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Three Dimensional Collagen Gels as a Cell Culture Matrix for the Study of Live Cells by Raman Spectroscopy, Franck Bonnier, Aidan Meade, S. Merzha, Peter Knief, Kunal Bhattacharya, Fiona Lyng, and Hugh Byrne

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Medium Mediated Effects Increase cell Killing in a Human Keratinocyte Cell Line Exposed to Solar Simulated Radiation, Fiona Lyng, Alanna Maguire, Brian Morrissey, and James E. Walsh

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Solar Simulated Radiation Induced Cell Death Depends on Spectral Distribution and Irradiance But Not Output Delivery, Alanna Maguire, Fiona Lyng, and James Walsh

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Spectroscopic and Chemometric Approaches to Radiobiological Analyses, Aidan Meade, Hugh Byrne, and Fiona Lyng

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Functional and Pathological Analysis of Biological Systems Using Vibrational Spectroscopy with Chemometric and Heuristic Approaches, Aidan Meade, Colin Clarke, Franck Bonnier, Kelvin W. Poon, Amaya Garcia, Peter Knief, Kamila Ostrowska, Lorenzo Salford, Haq Nawaz, Fiona Lyng, and Hugh Byrne

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Fourier Transform Infrared Microspectroscopy and Multivariate Methods for Radiobiological Dosimetry, Aidan Meade, Colin Clarke, Hugh Byrne, and Fiona Lyng

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Studies of Chemical Fixation Effects in Human Cell Lines Using Raman Microspectroscopy, Aidan Meade, Colin Clarke, Florence Draux, Ganesh Sockalingum, Michel Manfait, Fiona Lyng, and Hugh Byrne

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Mechanistic Studies of In Vitro Cytotoxicity of Poly(amidoamine) Dendrimers in Mammalian Cells, Sourav Prasanna Mukherjee, Fiona Lyng, Amaya Garcia, Maria Davoren, and Hugh Byrne

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Intracellular Localisation, Geno- and Cytotoxic Response of Poly N-isopropylacrylamide (PNIPAM) Nanoparticles to Human Keratinocyte (HaCaT) and Colon Cells (SW 480), Pratap Naha, Kunal Bhattacharya, Tiziana Tenuta, Kenneth Dawson, Iseult Lynch, Amaya Gracia, Fiona Lyng, and Hugh Byrne

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Reactive Oxygen Species Induced Cytokine Production and Cytotoxicity of PAMAM Dendrimers in J774a.1 Cells, Pratap Naha, Maria Davoren, Fiona Lyng, and Hugh Byrne

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Evaluation of the Potential of Raman Microspectroscopy for Prediction of Chemotherapeutic Response to Cisplatin in Lung Adenocarcinoma, Haq Nawaz, Franck Bonnier, Peter Knief, Orla Howe, Fiona Lyng, Aidan Meade, and Hugh Byrne

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Investigation of the Influence of High Risk Human Papillomavirus on the Biochemical Composition of Cervical Cancer Cells Using Vibrational Spectroscopy, Kamila Ostrowska, Alison Malkin, Aidan Meade, John O'Leary, Cara Martin, Cathy Spillane, Hugh Byrne, and Fiona Lyng

Submissions from 2009

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Reflection contributions to the dispersion artefact in FTIR spectra of single biological cells., Paul Bassan, Hugh Byrne, Joe Lee, Franck Bonnier, Colin Clarke, Paul Dumas, Ehsan Gazi, Michael Brown, Noel Clarke, and Peter Gardner

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TRIL, a Functional Component of the TLR4 Signaling Complex, Highly Expressed in Brain, Susan Carpenter, Thaddeus Carlson, Jerome Dellacasagrande, Amaya Garcia, Sharon Gibbons, Paul J. Hertzog, Anthony Lyons, Lih-Ling Lin, Marina A Lynch, Tom P. Monie, Caroline Murphy, Katherine Seidl, Christine Anne Wells, Aisling Dunne, and Luke O'Neill

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Dispersion medium modulates oxidative stress response of human lung epithelial cells upon exposure to carbon nanomaterial samples, Eva Herzog, Hugh Byrne, Maria Davoren, Alan Casey, Albert Duschl, and Gertie Janneke Oostingh

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SWCNT Suppress Inflammatory Mediator Responses in Human Lung Epithelium in Vitro, Eva Herzog, Hugh Byrne, Maria Davoren, Anke-Gabriele Lenz, Albert Duschl, and Gertie Janneke Oostingh

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Raman spectroscopy: a potential platform for the rapid measurement of carbon nanotube-induced cytotoxicity, Peter Knief, Colin Clarke, Eva Herzog, Maria Davoren, Fiona Lyng, Aidan Meade, and Hugh Byrne

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An integrated Approach to the Toxicity Assessment of Irish Marine Sediments Application of Porewater Toxicity Identification Evaluation (TIE) to Irish Marine Sediments, Ailbhe Macken, Michelle Giltrap, Barry Foley, Evin McGovern, Brendan McHugh, and Maria Davoren

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A Test Battery Approach to the Ecotoxicological Evaluation of Cadmium and Copper Employing a Battery of Marine Bioassays, Ailbhe Macken, Michelle Giltrap, Kim Ryall, Barry Foley, Evin McGovern, Brendan McHugh, and Maria Davoren

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Preparation, characterization and ecotoxicological evaluation of four environmentally relevant species of N-isopropylacrylamide and N-isopropylacrylamide-co-N-tert-butylacrylamide copolymer nanoparticles, Pratap Naha, Alan Casey, Tiziana Tenuta, Iseult Lynch, Kenneth Dawson, Hugh Byrne, and Maria Davoren

Submissions from 2008

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Single Walled Carbon Nanotubes Induce Indirect Cytotoxicity by Medium Depletion in A549 Lung Cells, Gordon Chambers, Alan Casey, Fiona Lyng, Maria Davoren, Eva Herzog (Thesis), and Hugh Byrne

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Effect of UVA Fluence Rate on Indicators of Oxidative Stress in Human Dermal Fibroblasts, James D. Hoerter, Christopher S. Ward, Kyle D. Bale, Admasu N. Gizachew, Rachelle Graham Rachelle Graham, Jaclyn Reynolds, Melanie E. Ward Melanie E. Ward, Chesca Choi, Jean-Leonard Kagabo, Michael Sauer, Tara Kuipers, Timothy Hotchkiss Timothy Hotchkiss, Nate Banner, Renee A. Chellson, Theresa Ohaeri, Langston Gant, and Leah Vanderhill

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A Model Compound Study: The Ecotoxicological Evaluation of five Organic Contaminants with a Battery of Marine Bioassays, Ailbhe Macken, Michelle Giltrap, Barry Foley, Evin McGovern, Brendan McHugh, and Maria Davoren

Submissions from 2007

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In Vitro Toxicity Evaluation of Single Walled Carbon Nanotubes on Human A549 Lung Cells, Maria Davoren, Eva Herzog, Alan Casey, Benjamin Cottineau, Gordon Chambers, Hugh Byrne, and Fiona Lyng

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A Novel Form of Ataxia Oculomotor Apraxia Characterized by Oxidative Stress and Aapoptosis Resistance, N. Gueven, O.J. Becherel, Orla L. Howe, P. Chen, J-F Haince, M.E. Oueliet, G.G. Poirier, N. Waterhouse, M. Fusser, B. Epe, J.M. De Murcia, G. De Murcia, C.H. McGowan, C. Mothersill, P. Grattan-Smith, and M.F. Lavin

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A New Approach to the Toxicity Testing of Carbon-based Nanomaterials: the Clonogenic Assay, Eva Herzog, Alan Casey, Fiona Lyng, Gordon Chambers, Hugh Byrne, and Maria Davoren

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Vibrational Spectroscopy for Pathology from Biochemical Analysis to Diagnostic Tool, Fiona Lyng, Eoghan O'Faolain, J. Conroy, Aidan Meade, Peter Knief, Brendan Duffy, M. Hunter, J. Byrne, P. Kelehan, and Hugh Byrne

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Modulation of Radiation Responses by Pre-Exposure to Irradiated Cell Conditioned Medium, Paula Maguire, Carmel Mothersill, B. McClean, C. Seymour, and Fiona Lyng

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Growth substrate induced functional changes elucidated by FTIR and Raman spectroscopy in in-vitro cultured human keratinocytes., Aidan Meade, Fiona Lyng, Peter Knief, and Hugh Byrne

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Increased Mitochondrial Mass in Cells with Functionally Compromised Mitochondria after Exposure to both Direct y Radiation and Bystander Factors, Sharon Nugent, Carmel Mothersill, C. Seymour, B. McClean, Fiona Lyng, and James Murphy

Submissions from 2006

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A Dose Threshold for a Medium Transfer Bystander Effect for a Human Skin Cell Line, Zhengfeng Liou, Carmel Mothersill, Fiona McNeill, Fiona Lyng, Soo Hyun Byun, Colin Seymour, and William Prestwich

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Apoptosis is Initiated in Human Keratinocytes Exposed to Signalling Factors from Microbeam Irradiated Cells, Fiona Lyng, Paula Maguire, A. Kilmurray, Carmel Mothersill, C. Shao, M. Folkard, and K. Prise

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The Involvement of Calcium and MAP Kinase Signaling Pathways in the Production of Radiation-Induced Bystander Effects, Fiona Lyng, Paula Maguire, B. McClean, C. Seymour, and Carmel Mothersill

Submissions from 2005

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Medium from Irradiated Cells Induces a Dose Dependent Expression of Mitochondrial Changes and BCL2 Responses in Unirradiated Human Keratinocytes, Paula Maguire, Carmel Mothersill, C. Seymour, and Fiona Lyng

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A Study Examining the Effects of Tissue Processing on Human Tissue Sections using Vibrational Spectroscopy, Eoghan O'Faolain, Mary Hunter, Joe Byrne, Peter Kellehan, Mary McNamara, Hugh Byrne, and Fiona Lyng

Submissions from 2004

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Ionizing Radiation Induces a Stress Response in Primary Cultures of Rainbow Trout Skin, Fiona Lyng, M. Lyons-Alcantara, P. Owell, Sharon Ni Shuilleabhain, Colin Seymour, D. Cottell, and Carmel Mothersill

Submissions from 2003

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Ecotoxicological research at DIT, Maria Davoren, Colm O'Dowd, and Sharon Ni Shuilleabhain

Submissions from 2002

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Initiation of Apoptosis in Cells Exposed to Medium from the Progeny of Irradiated Cells: a Possible Mechanism for "Bystander" induced Genomic Instability., Fiona Lyng, B. Maguire, B. McClean, C. Seymour, and Carmel Mothersill

Submissions from 2000

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Cell surface effects of androgens between 1 pM and 100 nM on rat sertoli cells and two human prostatic cell lines, LNCaP and PC3: evidence for two membrance receptors, Fiona Lyng, G. R. Jones, and F. F.G. Rommerts