Document Type
Article
Rights
Available under a Creative Commons Attribution Non-Commercial Share Alike 4.0 International Licence
Disciplines
1.4 CHEMICAL SCIENCES
Abstract
Aiming at the assessment of the pro-health, and especially anti-hypochlorite properties of Moringa oleifera species a representative, commercially available Moringaoleifera dietary supplement was used as a substrate for the preparation of aqueous Moringa extract. The anti-hypochlorite activity of the extract was assessed using the hypochlorite-specific coumarin-based fluorescence turn-off sensor, namely 7-diethylamino-coumarin-3-carboxylic acid (7-DCCA). This compound was synthesized via the Knoevenagel condensation of 4-diethylamino-2-hydroxybenzaldehyde with Meldrum’sacidandtheMoringaextractwasemployedasamediumandcatalyst. Moreover,thetotal phenoliccontent(TPC)aswellasthereactiveoxygenspecies(ROS)–scavengingabilityoftheaqueous Moringa extract were determined. The results obtained demonstrated the applicability of Moringa extract as an anti-hypochlorite agent. Additionally, the satisfactory yield of the 7-DCCA obtained suggests the usefulness of the extract as a catalyst and the reaction medium. The antioxidative potentialoftheextractwasnotablylowerthanthatofthestandard(TROLOX).DeterminationofTPC in 100 g of the dry weight (DW) of studied material revealed a high number of polyphones present.
DOI
https://doi.org/10.3390/molecules24183330
Recommended Citation
Starzak, K. et al (2019) Anti-Hypochlorite and Catalytic Activity of Commercially Available Moringa oleifera Diet Supplement, Molecules24(18),3330. doi:10.3390/molecules24183330
Publication Details
Molecules 2019, 24, 3330; doi:10.3390/molecules24183330