Solid-state NMR - a complementary technique for protein framework characterization

Authors

• Linda Cerofolini, Università degli Studi di Firenze
• Kiefer O. Ramberg, School of Chemical and BioPharmaceutical Science
• Luis C. Padilla, Università degli Studi di Firenze
• Paweł Antonik, University of Galway
• Enrico Ravera, Università degli Studi di Firenze
• Claudio Luchinat, Università degli Studi di Firenze
• Marco Fragai, Università degli Studi di Firenze
• Peter B. Crowley, University of Galway

ORCID

• Kiefer O. Ramberg: 0000-0002-3991-4809

Abstract

Protein frameworks are an emerging class of biomaterial with medical and technological applications. Frameworks are studied mainly by X-ray diffraction or scattering techniques. Complementary strategies are required. Here, we report solid-state NMR analyses of a microcrystalline protein-macrocycle framework and the rehydrated freeze-dried protein. This methodology may aid the characterization of low-crystallinity frameworks.

DOI Link

10.1039/d2cc05725e

Publication Date

2022-12-15

Publication Title

Chemical Communications

Volume

59

Issue

6

ISSN

1359-7345

First Page

776

Last Page

779

Deposit Date

2026-08-05

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Additional Links

https://www.scopus.com/pages/publications/85144879087

Recommended Citation

Cerofolini, L., Ramberg, K., Padilla, L., Antonik, P., Ravera, E., Luchinat, C., Fragai, M., & Crowley, P. (2022) 'Solid-state NMR - a complementary technique for protein framework characterization', Chemical Communications, 59(6), pp. 776-779. Available at: 10.1039/d2cc05725e