Document Type

Article

Rights

Available under a Creative Commons Attribution Non-Commercial Share Alike 4.0 International Licence

Disciplines

Ophthalmology

Publication Details

Vision Research, Volume 50, Issue 13, 18 June 2010, Pages 1249-1256

Abstract

This study was designed to assess whether macular pigment optical density (MPOD) is associated with visual performance. One hundred and forty-two young healthy subjects were recruited. Macular pigment optical density and visual performance were assessed by psychophysical tests including best corrected visual acuity (BCVA), mesopic and photopic contrast sensitivity, glare sensitivity, photostress recovery time (PRT). Measures of central visual function, including BCVA and contrast sensitivity, were positively associated with MPOD (p < 0.05, for all). Photostress recovery and glare sensitivity were unrelated to MPOD (p > 0.05). A longitudinal, placebo-controlled and randomized supplementation trial will be required to ascertain whether augmentation of MPOD can influence visual performance.

DOI

https://doi.org/10.1016/j.visres.2010.04.009. Epub 2010 Apr 13

Funder

Bausch & Lomb Inc. and Enterprise Ireland under the Innovation Partnerships Programme

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