Author ORCID Identifier

0000-0002-1735-8610

Document Type

Article

Rights

This item is available under a Creative Commons License for non-commercial use only

Disciplines

Atomic, Molecular and Chemical Physics, Pathology, Dentistry, oral surgery and medicine, Health-related biotechnology

Publication Details

“Biomedical Applications of Vibrational Spectroscopy: Oral Cancer Diagnostics”, Hugh J. Byrne, Isha Behl, Genecy Calado, Ola Ibrahim, Mary Toner, Sheila Galvin, Claire M. Healy, Stephen Flint and Fiona M. Lyng, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 252, 119470 (2021)

Abstract

Vibrational spectroscopy, based on either infrared absorption or Raman scattering, has attracted increasing attention for biomedical applications. Proof of concept explorations for diagnosis of oral potentially malignant disorders and cancer are reviewed, and recent advances critically appraised. Specific examples of applications of Raman microspectroscopy for analysis of histological, cytological and saliva samples are presented for illustrative purposes, and the future prospects, ultimately for routine, chairside in vivo screening are discussed.

DOI

https://doi.org/10.1016/j.saa.2021.119470


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