Author ORCID Identifier
0000-0002-1735-8610
Document Type
Article
Rights
Available under a Creative Commons Attribution Non-Commercial Share Alike 4.0 International Licence
Disciplines
Pathology, Health-related biotechnology
Abstract
Vibrational spectroscopy, based on either infrared absorption or Raman scattering, has attracted increasing attention for biomedical applications. Proof of concept explorations for diagnosis of oral potentially malignant disorders and cancer are reviewed, and recent advances critically appraised. Specific examples of applications of Raman microspectroscopy for analysis of histological, cytological and saliva samples are presented for illustrative purposes, and the future prospects, ultimately for routine, chairside in vivo screening are discussed.
DOI
https://doi.org/10.1016/j.saa.2021.119470
Recommended Citation
Byrne, H. J. et al. (2021) Biomedical Applications of Vibrational Spectroscopy: Oral Cancer Diagnostics, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 252, 119470 (2021) DOI:10.1016/j.saa.2021.119470
Included in
Biological and Chemical Physics Commons, Diagnosis Commons, Oral Biology and Oral Pathology Commons, Other Analytical, Diagnostic and Therapeutic Techniques and Equipment Commons
Publication Details
“Biomedical Applications of Vibrational Spectroscopy: Oral Cancer Diagnostics”, Hugh J. Byrne, Isha Behl, Genecy Calado, Ola Ibrahim, Mary Toner, Sheila Galvin, Claire M. Healy, Stephen Flint and Fiona M. Lyng, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 252, 119470 (2021)