Synthesis and Characterisation of Macrocycles Containing both Tetrazole and Pyridine Functionalities

Authors

Adrienne Fleming, Technological University Dublin
Jackie Gaire, Technological University Dublin
Fintan Kelleher, Technological University DublinFollow
John McGinley, NUI Maynooth
Vickie McKee, Loughborough University

Document Type

Article

Rights

Available under a Creative Commons Attribution Non-Commercial Share Alike 4.0 International Licence

Disciplines

Organic Chemistry

Publication Details

Tetrahedron

Abstract

The syntheses of tetra-tetrazole macrocycles containing at least one 2,6-bis(tetrazole)pyridine unit, linked by a variety of n-alkyl (n = 3, 5, 7 or 9 carbon atoms) chain lengths, are described. There has been no previous incorporation of the pyridine moiety into a tetra-tetrazolophane macrocycle. The crystal structure of one such tetra-tetrazole macrocycle has also been structurally characterised and revealed a bowl-shaped conformation.

Recommended Citation

Fleming, A., Gaire, J., Kelleher, F., McGinley, J., McKee, V.: Synthesis and Characterisation of Macrocycles Containing both Tetrazole and Pyridine Functionalities. Tetrahedron,vol. 67 (8), 6 May 2011,p.3260–3266

Funder

Irish Government