Document Type
Article
Rights
Available under a Creative Commons Attribution Non-Commercial Share Alike 4.0 International Licence
Disciplines
1.4 CHEMICAL SCIENCES, 1.6 BIOLOGICAL SCIENCES, Biochemistry and molecular biology, Biophysics, 3. MEDICAL AND HEALTH SCIENCES
Abstract
A series of complexes incorporating Zn(II), Cu(II), and Pd(II) ions, and 4-(5-heptyl-1,3,4-thiadiazol-2-yl)benzene-1,3-diol (L1) as model ligand, was synthesized in order to examine the nature of potential interactions between biologically active ligands, 1,3,4-thiadiazoles and metal ions with proven biological relevance. The structures of the compounds isolated were characterized using a number of spectroscopic methods including IR, Uv–vis, AAS, steady state and time-resolved fluorescence (TRF). The results obtained suggest that the L1-Zn(II) and L1-Pd(II) complexes consist of one molecule of L1 and one acetate ion acting as ligands, while the L1-Cu(II) complex adapts a 2:1 (L1: metal) stoichiometry. The coordination of L1 to metal ions occurs most likely via one of the deprotonated hydroxyl groups of the resorcinyl moiety and one of the N atoms of the thiadiazole heterocycle.
DOI
https://doi.org/10.1016/j.molstruc.2016.08.042
Recommended Citation
Dariusz Karcz, Arkadiusz Matwijczuk, Bożena Boroń, Bernadette Creaven, Leszek Fiedor, Andrzej Niewiadomy, Mariusz Gagoś, Isolation and spectroscopic characterization of Zn(II), Cu(II), and Pd(II) complexes of 1,3,4-thiadiazole-derived ligand, Journal of Molecular Structure, Volume 1128, 2017, Pages 44-50, ISSN 0022-2860, DOI: 10.1016/j.molstruc.2016.08.042.
Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-No Derivative Works 4.0 International License.
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Biochemistry, Biophysics, and Structural Biology Commons, Chemistry Commons, Medicine and Health Sciences Commons
Publication Details
Published version:
https://doi.org/10.1016/j.molstruc.2016.08.042