ORCID
- Hugh James Byrne: 0000-0002-1735-8610
Abstract
Vibrational spectroscopy, specifically based on infrared absorption and Raman scattering, has emerged as a viable alternative to current biomedical diagnostic techniques, providing label-free, biochemically based early disease detection and precise diagnosis. Potential applications, specifically in stomatology and oral pathology, are described, highlighting chairside analysis of saliva, in vivo probing of suspicious lesions and surgical margins, and histology laboratory-based analyses of biopsy samples. Key challenges to implementation are discussed, and perspectives on future deployment of the techniques are presented.
Keywords
Clinical translation, Infrared absorption, Oral lesion, Raman scattering, Saliva, Surgical margin, Tissue biopsy, Vibrational spectroscopy
DOI Link
Publication Date
2026-01-01
Publication Title
International Dental Journal
Volume
76
Issue
6
ISSN
0020-6539
Deposit Date
2026-11-09
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Additional Links
Recommended Citation
das Chagas e Silva de Carvalho, L., & Byrne, H. (2026) 'From Bench to Chairside: Vibrational Spectroscopy in Stomatology and Oral Pathology', International Dental Journal, 76(6). Available at: 10.1016/j.identj.2026.111165