Document Type
Article
Rights
Available under a Creative Commons Attribution Non-Commercial Share Alike 4.0 International Licence
Disciplines
2. ENGINEERING AND TECHNOLOGY, Medical engineering
Abstract
Over the past decade the introduction of drug-eluting stents (DESs) has revolutionised the treatment of coronary artery disease. However, in recent years concern has arisen over the long-term safety and efficacy of DESs due to the occurrence of late adverse clinical events such as stent thrombosis. With this concern in mind, research and development is currently centred on increasing the long-term safety and efficacy of DESs. The aim of this paper is to provide a thorough review of currently approved and promising investigational DESs. With dozens of companies involved in the development of new and innovative anti-restenotic agents, polymeric coatings and stent platforms, it is intended that this review paper will provide a clear indication of how DESs are currently evolving and prove a valuable reference tool for future research in this area.
DOI
https://doi.org/10.1016/j.medengphy.2010.10.009
Recommended Citation
Martin, D., Boyle, F.: 'Drug-eluting stents for coronary artery disease: a review, Medical Engineering & Physics (2011) Volume: 33, Issue: 2, Pages: 148-163. PubMed 21075668. doi: 10.1016/j.medengphy.2010.10.009
Publication Details
Medical Engineering & Physics (2011). Volume:33, Issue:2, Pages: 148-163. PubMed: 21075668. Available from www..ncbi.nlm.nih.gov