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1.6 BIOLOGICAL SCIENCES, 3. MEDICAL AND HEALTH SCIENCES
We describe a PCR-assay differentiating Streptococcus pneumoniae from closely-related species of the Mitis group of the genus Streptococcus and identification of pneumococcus clinical isolates, based on the “Xisco” gene discriminatory marker. The complete “Xisco” gene sequence was observed in all S. pneumoniae genomes analyzed and absent in all non-pneumococcus genomes.
Francisco Salvà-Serra, Gwendolyn Connolly, Edward R.B. Moore, Lucia Gonzales-Siles, Detection of “Xisco” gene for identification of Streptococcus pneumoniae isolates, Diagnostic Microbiology and Infectious Disease, Volume 90, Issue 4, 2018,Pages 248-250, ISSN 0732-8893, DOI: 10.1016/j.diagmicrobio.2017.12.003.