Document Type

Article

Rights

This item is available under a Creative Commons License for non-commercial use only

Disciplines

1.6 BIOLOGICAL SCIENCES

Publication Details

Journal of Biological Chemistry

Abstract

Background: Lysine acetylation is a major post-translational modification of proteins.

Results: Human glycine N-acyltransferase-like 2 is regulated by acetylation/deacetylation of lysine 19.

Conclusion: Reversible lysine acetylation is important in regulating the activity and function of human glycine N-acyltransferases.

Significance: Our study links post-translational modification of proteins with the production of lipid signaling molecules, the N-acyl glycines.

DOI

https:doi.org/10.1074/jbc.M112.347260

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