Abstract
The escalation of ecological degradation, marked by climatic instability, precipitous biodiversity loss, and systemic chemical infiltration, necessitates a shift toward integrated biotechnological intervention. This analysis considers how the trajectory of diverse advanced methodologies, including environmental DNA (eDNA) surveillance, CRISPR-based genetic restitution, and synthetic biology-driven bioremediation, might be synthesized into a unified Planetary Health Framework. By exploring the convergence of high-precision genomic engineering, AI-augmented bioinformatic modeling, and the tenets of a circular bio-economy, we examine the capacity of technological intervention to ameliorate ecological stressors and restore critical ecosystems. Moving beyond the constraints of conventional conservation, this discourse explores frontier solutions in climate-resilient agrotechnology, photo-driven biomanufacturing, and technologically integrated urban ecology, highlighting the criticality of microbiome modulation and comprehensive genomic repositories in stabilizing the biosphere. By reconciling molecular-level precision with macro-scale systems ecology, this framework points to a trajectory for sustainable development where technological scalability is constrained by, yet optimized for, planetary boundaries. Ultimately, this review addresses the imperatives of ethical oversight and highlights the multi-sectoral governance architectures required for the responsible global deployment of these "living technologies."
Keywords
Bioremediation, Circular Bioeconomy, Environmental Genomics, Planetary Health, Synthetic Biology
DOI Link
Publication Date
2026-04-01
Publication Title
Eurobiotech Journal
Volume
10
Issue
2
First Page
81
Last Page
102
Deposit Date
2026-07-27
Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-No Derivative Works 4.0 International License.
Additional Links
Recommended Citation
Yildirim, Duygu T.; Baki Yildirim, A.; Martin, Donald; Beccari, Tommaso; Vicente, Oscar; Radecka, Iza; Tchuenbou-Magaia, Fideline; Marks, Robert; Lal, Ratnesh; Prakash, Satya; Mechler, Adam; Milkov, Mario Petrov; Georgieva, Svetlana Fotkova; Iliev, Ilia; Kaneva, Radka; Gokce, Nuriye; Yaneva, Galina Aleksieva; Agova, Nadya Vasileva; Ivanova, Nikoleta Dobromirova; Sahin, Izem Olcay; Tsvetkova, Mariya Kiryakova; Iliev, Ivelin Rosenov; Salzet, Michel; Ko, Kisung; Maffia, Michele; Bertelli, Matteo; Fournier, Isabelle; Pojskic, Lejla; Sun, Qun; Nei, Lembit; and Armgrisson, Reynir, "Integrated Biotechnological Strategies for Planetary Health and Ecosystem Restoration" (2026). Research Outputs: 2025-Present. 1.
https://arrow.tudublin.ie/gcbioro/1