Abstract
The escalation of ecological degradation, marked by climatic instability, precipitous biodiversity loss, and systemic chemical infiltration, necessitates a shift toward integrated biotechnological intervention. This analysis considers how the trajectory of diverse advanced methodologies, including environmental DNA (eDNA) surveillance, CRISPR-based genetic restitution, and synthetic biology-driven bioremediation, might be synthesized into a unified Planetary Health Framework. By exploring the convergence of high-precision genomic engineering, AI-augmented bioinformatic modeling, and the tenets of a circular bio-economy, we examine the capacity of technological intervention to ameliorate ecological stressors and restore critical ecosystems. Moving beyond the constraints of conventional conservation, this discourse explores frontier solutions in climate-resilient agrotechnology, photo-driven biomanufacturing, and technologically integrated urban ecology, highlighting the criticality of microbiome modulation and comprehensive genomic repositories in stabilizing the biosphere. By reconciling molecular-level precision with macro-scale systems ecology, this framework points to a trajectory for sustainable development where technological scalability is constrained by, yet optimized for, planetary boundaries. Ultimately, this review addresses the imperatives of ethical oversight and highlights the multi-sectoral governance architectures required for the responsible global deployment of these "living technologies."
Keywords
Bioremediation, Circular Bioeconomy, Environmental Genomics, Planetary Health, Synthetic Biology
DOI Link
Publication Date
2026-04-01
Publication Title
Eurobiotech Journal
Volume
10
Issue
2
First Page
81
Last Page
102
Deposit Date
2026-07-27
Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-No Derivative Works 4.0 International License.
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Recommended Citation
Yildirim, D., Baki Yildirim, A., Martin, D., Beccari, T., Vicente, O., Radecka, I., Tchuenbou-Magaia, F., Marks, R., Lal, R., Prakash, S., Mechler, A., Milkov, M., Georgieva, S., Iliev, I., Kaneva, R., Gokce, N., Yaneva, G., Agova, N., Ivanova, N., Sahin, I., Tsvetkova, M., Iliev, I., Salzet, M., Ko, K., Maffia, M., Bertelli, M., Fournier, I., Pojskic, L., Sun, Q., Nei, L., & Armgrisson, R. (2026) 'Integrated Biotechnological Strategies for Planetary Health and Ecosystem Restoration', Eurobiotech Journal, 10(2), pp. 81-102. Available at: 10.2478/ebtj-2026-0009