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In the United States, approximately 17,000 people per year are diagnosed with brain tumors, the leading cause of death from cancers in children ages 1-15 year (1,2). Gliomas are the most prevalent type of brain tumors in adults, affecting 3.2/100,000 persons/yr in the United States (www.CBTRUS.org). In spite of advances in surgery, chemotherapy, and radiotherapy, the mean survival time of patients post-diagnosis remains approximately 9-12 months.
Castro, M.G., Curtin, J.F. & King, G.D., (2006). Novel Gene Therapeutic Approaches to Brain Cancer. Gene Therapy for Neurological Disorders, Chapter 13. (Taylor & Francis Group). doi:10.21427/e3bq-qp57
National Institute of Health, Bram and Elaine Goldsmith Chair in Gene Therapeutics, The Linda Tallen and David Paul Kane Annual Fellowship, Board of Governors at Cedars Sinai Medical Center.