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1.7 OTHER NATURAL SCIENCES
Purpose To study changes in anterior segment morphometry after uneventful phacoemulsification cataract surgery, and to investigate whether there is a relationship between any observed changes and intraocular pressure (IOP) reduction after the procedure. Methods The anterior chamber depth (ACD), anterior chamber volume (ACV), anterior chamber angle (ACA), central corneal thickness (CCT), and IOP were measured in 101 non-glaucomatous eyes before and after uneventful phacoemulsification cataract surgery. Results After cataract surgery, the mean ACD, ACV, and ACA values increased by 1.08mm, 54.4mm3, and 13.11, respectively, and the mean IOP (corrected for CCT) decreased by 3.2mmHg. The predictive value of a previously described index (preoperative ACD/preoperative IOP (corrected for CCT) or CPD ratio) for IOP (corrected for CCT) reduction after cataract surgery was confirmed, reflected in an r2 value of 23.3% between these two parameters (Po0.001). Other indices predictive of IOP reduction after cataract surgery were also identified, including preoperative IOP/preoperative ACV and preoperative IOP/preoperative ACA, reflected in r2 values of 13.7 and 13.7%, respectively (Po0.001 and Po0.001, respectively). Conclusions Our study confirms the predictive value of the CPD ratio for IOP reduction after cataract surgery, and may contribute to the decision-making process in patients with glaucoma or ocular hypertension. Furthermore, two novel indices of preoperative parameters that are predictive for IOP reduction after cataract surgery were identified, and enhance our understanding of the mechanisms underlying IOP changes after this procedure.
Dooley, J., Charalampidou, S., Malik, A., Loughman, J., Molloy, L., Beatty, S.: Changes in Intraocular Pressure and Anterior Segment Morphometry After Uneventful Phacoemulsification Cataract Surgery. Eye, pp.1-9. 2010. doi:10.1038/eye.2009.339