Author ORCID Identifier
Available under a Creative Commons Attribution Non-Commercial Share Alike 4.0 International Licence
2.3 MECHANICAL ENGINEERING, Medical engineering
In this paper the area-difference-energy spring-particle (ADE-SP) red blood cell (RBC) structural model developed by Chen and Boyle is coupled with a lattice Boltzmann flux solver to simulate RBC dynamics. The novel ADE-SP model accounts for bending resistance due to the membrane area difference of RBCs while the lattice Boltzmann flux solver offers reduced computational runtimes through GPU parallelisation and enabling the employment of non-uniform meshes. This coupled model is used to simulate RBC dynamics and predictions are compared with existing experimental measurements. The simulations successfully predict tumbling, tank-treading, swinging and intermittent behaviour of an RBC in shear flow, and demonstrate the capability of the model in capturing in-flow RBC behaviours.
Dr. Brendan Walsh & Prof. Fergal J. Boyle (2022) In-Flow dynamics of an area-difference-energy spring-particle red blood cell model on non-uniform grids, Computer Methods in Biomechanics and Biomedical Engineering, 25:1, 52-64, DOI: 10.1080/10255842.2021.1931845
Technological University Dublin